A computer model for the 30S ribosome subunit
نویسندگان
چکیده
منابع مشابه
A structural model for the assembly of the 30S subunit of the ribosome.
The order in which proteins bind to 16S rRNA, the assembly map, was determined by Nomura and co-workers in the early 1970s. The assembly map shows the dependencies of binding of successive proteins but fails to address the relationship of these dependencies to the three-dimensional folding of the ribosome. Here, using molecular mechanics techniques, we rationalize the order of protein binding i...
متن کاملSpatial configuration of ribosomal proteins: a computer-generated model of the 30S subunit.
SPATIAL CONFIGURATION OF RIBOSOMAL PROTEINS: A COMPUTER-GENERATED MODEL OF THE 30S SUBUNIT Alex Bollen*, R.J. Cedergren, David Sankoff and Guy Lapalme D6partement de biochimie et Centre de recherches math~matiques Universit~ de Montreal, Case Postale 6128, Montreal H3C 3J7 Received june 23,1974 Summary: Much data are currently being produced pertinent to spatial relationships among ribosomal pr...
متن کاملInteraction of Era with the 30S ribosomal subunit implications for 30S subunit assembly.
Era (E. coliRas-like protein) is a highly conserved and essential GTPase in bacteria. It binds to the 16S ribosomal RNA (rRNA) of the small (30S) ribosomal subunit, and its depletion leads to accumulation of an unprocessed precursor of the 16S rRNA. We have obtained a three-dimensional cryo-electron microscopic map of the Thermus thermophilus 30S-Era complex. Era binds in the cleft between the ...
متن کاملThe GTP-binding protein YqeH participates in biogenesis of the 30S ribosome subunit in Bacillus subtilis.
Bacterial genome sequencing has revealed a novel family of P-loop GTPases that are often essential for growth. Accumulating evidence suggests that these proteins are involved in biogenesis of the 30S or 50S ribosomal subunits. YqeH is a member of this Obg/Era GTPase family, with its function remains to be uncovered. Here, we present results showing that YqeH is involved in the 30S subunit bioge...
متن کاملinvestigating the feasibility of a proposed model for geometric design of deployable arch structures
deployable scissor type structures are composed of the so-called scissor-like elements (sles), which are connected to each other at an intermediate point through a pivotal connection and allow them to be folded into a compact bundle for storage or transport. several sles are connected to each other in order to form units with regular polygonal plan views. the sides and radii of the polygons are...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1980
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(80)85009-0